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In the last 100 years alone, there have been four major influenza pandemics and multiple epidemics, including the Spanish flu in 1918, with an estimated 1750 million deaths worldwide 3 , as well as the Asian and Hong Kong flu in 1957/58 and 1968/69 with one to four million deaths worldwide 4

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SR-AI appears to preferentially recognize more rigorously oxidized LDL and seems to primarily recognize modified lysine residues like MDA-lysines

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